The Science Behind Attune’s Innovative Therapies

At Attune Biotech, our commitment to revolutionizing healthcare is rooted in a deep understanding of the underlying science. We modulate the immune system and address inflammation at its source with our lead therapeutic, which works through multiple pathways. Complementing this, our innovative AI-driven platform provides continuous monitoring and personalized care, creating a synergistic approach to transform the lives of patients with chronic diseases.

Multifaceted Immune Modulation

JKB-122 is not a typical drug; it’s a sophisticated immune modulator that exerts its effects through multiple, interconnected pathways. This multifaceted approach sets it apart, allowing for a comprehensive and balanced effect on the immune system. key mechanisms include:

Key Binding Properties:

Interacting with the Body’s Receptors

JKB-122 exhibits rapid cellular diffusion, binds to both surface and nuclear opioid receptors, and interacts with multiple cellular receptors and proteins, leading to complex immunomodulatory effects.

Pattern Recognition Receptor (PRR) Modulation

Calming Overactive Immune Responses

JKB-122 reduces PRR signal strength, dampens cellular activation, helps cells return to steady state, decreases inflammatory signals (cytokines and interferons), and promotes immune system balance.

Nuclear Pathway

DAMP Regulation

JKB-122 reduces the release of Damage-Associated Molecular Patterns (DAMPs), decreasing inflammation.

Liver X Receptor (LXR) Interaction

Regulating Inflammation at the Cellular Level

JKB-122 binds to LXR nuclear receptors, modulating gene expression involved in cholesterol metabolism, inflammation control, and immune response regulation, ultimately reducing pro-inflammatory cytokine production and addressing inflammation at the cellular level.

Immune System Effects

Restoring Immune Balance and Function

JKB-122 restores the balance between cellular (Th1) and humoral (Th2) immunity, regulates T-helper cell cytokine production, and enhances natural killer cell function.

Anti-inflammatory Effects

Reducing Inflammation and Promoting Healing

JKB-122 decreases systemic inflammation, reduces inflammatory mediators, promotes tissue healing, and supports homeostasis.

Unique Features

Multifaceted Action and Safety Profile

JKB-122 works through multiple parallel pathways, affects both surface and nuclear receptors, combines immediate and delayed effects, promotes systemic immune balance, is a natural immune system modulator, and has a well-established safety profile with minimal side effects at low doses.

Key Differentiators

Efficacy, Safety, and Value

JKB-122 provides comprehensive immune modulation through a non-immunosuppressive approach, offering physiological immune enhancement with multiple therapeutic applications, a strong safety profile, and cost-effectiveness.

effective treatment beyond medication

Attune’s Integrated AI Healthcare Platform

Attune Biotech recognizes that effective treatment extends beyond medication. That’s why we’ve developed our groundbreaking 25/7 Digital AI Driven Platform, a critical component of our comprehensive approach to patient care. This platform is more than just a monitoring tool; it’s a sophisticated system designed to:

24/7 Real-Time Health Insights

Continuous Monitoring and Enhanced Communication

Attune patients gain 12-month access to an AI-driven digital telehealth platform that enables continuous patient monitoring and medication adherence. The platform also enhances communication between patients and providers, ensuring timely support and intervention.

AI-Powered Personalized Health Management

Predictive Insights for Improved Outcomes

The platform leverages AI to provide personalized mental health support and pain tracking and management. By analyzing patient data, the AI helps to improve clinical outcomes and the overall patient experience.

Proactive Intervention and Crisis Management

Early Detection and Timely Support

While continuously monitoring patients, the platform can support the early detection of potential issues, allowing for timely intervention and potentially preventing crises. This proactive approach contributes to improved patient safety and well-being.

Personalized Treatment Optimization

Integrated Care for Maximum Impact

Attune’s integrated care model combines immune-restorative therapies with the digital platform to optimize clinical outcomes and drive long-term treatment adherence. This comprehensive approach is particularly beneficial for patients with chronic conditions.

By combining our innovative pharmaceutical approach with a tailored digital health solution, Attune is able to deliver a comprehensive and differentiated therapy package that addresses the multifaceted needs of patients – setting a new standard for chronic disease management.

Frequently Asked Questions

What are immune-restorative therapies?

Immune-restorative therapies are innovative treatments designed to address the underlying causes of immune dysfunction. Unlike traditional therapies that merely suppress symptoms, these therapies aim to restore the immune system’s natural balance and enhance overall health.

How do these therapies work?

Our therapies work by targeting the root causes of immune dysfunction, utilizing advanced biotechnology to restore immune balance. This approach reduces inflammation and promotes long-term health improvements, both physically and mentally, ensuring a holistic treatment experience.

Who can benefit from these therapies?

Individuals experiencing chronic diseases can benefit significantly from our therapies.

Are there any side effects?

While our therapies are designed to be safe and effective, some individuals may experience mild side effects. These can include temporary fatigue or mild inflammation as the body adjusts to the treatment, but serious side effects are rare.

How long does it take to see results?

The time to see results can vary based on individual health conditions and the specific therapy used. Generally, patients may start noticing improvements within a few weeks, with more significant benefits observed over several months of consistent treatment.